About
Summary
commitment to research. Rather than viewing my education as a series of courses, I have
treated each stage as a steppingstone to refine my laboratory skills and theoretical knowledge.
My primary ambition is to transition into a doctoral program, where I can apply this foundation
to a long-term research project.
I possess a strong background in molecular biology, experimental design and data analysis. I
have experience in laboratory research, and I am interested in the application of biomedical
sciences to human health, exercise physiology and sports performance.
In addition to maintaining a strong academic record throughout my degree, I have also earned
an Advanced Certificate in Information Management and Research Skills and hold a C1
Advanced English certification from the University of Cambridge.
Positions
Intership Jun 2024 - Aug 2024
Quality control internship at FINSA (June and July 2024). During my internship in the Quality Assurance Department at FINSA, I supported quality
control activities and participated in the analysis and interpretation of production data. I was
involved in monitoring and evaluating quality indicators, contributing to the preparation of
technical documentation and reports. Working under standardized procedures and quality
management guidelines, I developed strong attention to detail and analytical skills.
Additionally, I collaborated with multidisciplinary teams to identify quality-related issues and
support the implementation of effective solutions aimed at continuous process improvement.
Intership Feb 2024 - Jun 2026
I have served a internship as a research intern at the Epitranscriptomics & Ageing (EpiAgeing)
Group at CIMUS (February 2025 – Present).
My undergraduate thesis, titled "Study of m6A regulators in RNA in accelerated aging and in
rejuvenation through somatic cell reprogramming," was conducted at the CIMUS research
center. The project addressed the role of m6A (N6-methyladenosine) in two opposing
biological contexts: accelerated aging (Hutchinson-Gilford Progeria Syndrome - HGPS) and
cellular rejuvenation (iPSCs generation).
Through bioinformatic analysis, I determined that m6A regulators are not transcriptionally
altered in HGPS models. Experimentally, I demonstrated that the expression of m6A "writers"
(Mettl3 and Mettl14) increases during reprogramming and that the knockdown of Mettl3
significantly reduces the efficiency of obtaining pluripotent cells.
Education
Universidade de Santiago de Compostela 2025 - 2026
Field of study: Biomedical Investigation
Degree: Master's degree in Biomedical Investigation
My Master's Thesis focused on how inhibition of the spliceosome by Pladenolide B (PlaB)
reprograms mouse pluripotent stem cells towards a totipotent state, generating totipotent-like
blastomere cells. These cells closely mimic blastomeres of the 2-4 cell stages, exhibiting
activation of key totipotency markers such as MERVL and Zscan4, alongside the silencing of
core pluripotency genes. Using a combination of techniques, including flow cytometry,
timelapse imaging, RTqPCR, and automated image analysis with CellProfiler, their
transcriptional and molecular profile was characterized. Additionally, the role of transposable
elements, particularly MERVL, in regulating chromatin accessibility and neighboring gene
expression during the 2-cell stage was investigated. The contribution of NSUN RNA
methyltransferases to epitranscriptomic regulation and their involvement in epigenetic
remodeling during preimplantation development were also explored.
Universidade de Santaigo de Compostela 2021 - 2025
Field of study: Biochemistry
Degree: Bachelor's degree in Biochemistry
My undergraduate thesis focused on the study of epitranscriptomic regulators of the N6
methyladenosine (m⁶A) modification in RNA, a key mechanism in the post-transcriptional
control of gene expression. The research addressed two opposing biological scenarios:
accelerated aging, using the Hutchinson-Gilford progeria syndrome (HGPS) model, and
cellular rejuvenation, through somatic reprogramming into induced pluripotent stem cells
(iPSCs).
In the first part of the study, a transcriptomic dataset from mouse fibroblasts homozygous for
progerin expression was analyzed using bioinformatic tools such as BioJupies and Morpheus.
The expression levels of Mettl3, Mettl14, Mettl16, Fto, and Alkbh5 showed no significant
differences between HGPS and control samples. This suggests that the functional regulation
of these enzymes may not rely solely on transcriptional expression.
Skills
My research experience has allowed me to develop a comprehensive technical profile,
encompassing the following specialized methodologies essential for doctoral-level research:
• Molecular Biology & Transcriptomics: Proven proficiency in RNA extraction, cDNA
synthesis, and gene expression analysis via quantitative PCR (qPCR).
• Advanced Cell Culture & Virology: Extensive experience in the maintenance and
manipulation of mammalian cell lines (including fibroblasts and HEK293T). I am skilled
in the generation of lentiviral particles and the implementation of loss-of-function
studies through shRNA-mediated genetic silencing.
• Cellular Reprogramming & Characterization: Hands-on expertise in somatic cell
reprogramming using Yamanaka factors. Competent in characterizing cellular states
through flow cytometry (FACS) for pluripotency markers (e.g., Nanog) and high-content
analysis using advanced fluorescence microscopy.
• Computational Biology & Bioinformatics: Ability to process and interpret complex
transcriptomic datasets using bioinformatic platforms such as BioJupies and Morpheus
for differential expression and pathway analysis.
• Scientific Communication & Languages: Strong aptitude for the synthesis and
presentation of experimental data. I possess advanced scientific writing skills in
Galician, Spanish, and English (C2 level), enabling effective communication within
international research environments.
Professional interests
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