About
Summary
I am a person that is applied with dedication, commitment and love in everything I do. My passion for chemistry and biology have led to focus my studies in chemistry and pharmaceutical biology. I am a versatile and determined person to want to expand my knowledge in this fascinating field through training experience.
Thanks to my experiences I developed a high sense of duty, reaching the meaning of teamwork and problem solving
Positions
Theist ( 1 year) Oct 2015 - Oct 2016
Experimental Thesis, Università degli Studi di Catania, Dep. Drug Science
The aim of my experimental thesis for Master degree was the development of new synthetic method in order to obtain the labeling of a selective Sigma-1 receptor ligand with [11C] in the final step of the reaction scheme for positron emission tomography imaging. Indeed the aforementioned Sigma-1 receptor ligand (unlabeled) was previously developed and evaluated for its binding affinity in other work (Bioorganic & Med. Chem. 2016, 24, 3149–3156). The synthetic protocol followed in this work for the synthesis of this ligand is not particularly advantageous for radiolabeling of compound. Thus, I contributed with my team for design and development of a new synthetic scheme in order to obtain an increasing of concentration of labeled ligand and extended time to utilize the radioactivity of radiotracer. Furthermore, we have supplied the reaction and purification conditions that would lead to the development of PET probe, in fact the final step of reaction scheme will be made in partner structure.
Education
University 2010 - 2016
Field of study: Medicinal Chemistry
Degree: Master's Degree
Skills
Organic synthesis:
Good knowledge of the most common organic chemistry synthesis techniques. Reactions under nitrogen, at reflux, 0° C, vacuum drying. Multistep liquid phase small molecules and short peptides synthesis.
Purification processes:
Good application in common purification techniques as glass column liquid chromatography, MPLC, TLC, LLE and crystallization.
Interpretation of spectra:
During my studies I have acquired the knowledge required to interpretation of spectra of the main spectroscopic methods as 1H NMR, 13C NMR, MS, IR. Therefore, during my research thesis activity, I have assisted my supervisors for analysis with 200Hz and 500Hz NMR instruments.
Communication:
Can deliver presentations in both oral and poster format
IT:
Proficient with Apple OS, Microsoft Windows OS, Microsoft Office Suite. Computational Chemistry Applications: Chemdraw, ACD labs. Bibliographical Research Ability: Pubmed, SciFinder.
Language skills:
Good English practice (listening, speaking and writing)
Skills as supervisor:
Previous experience as assistant in the Laboratory of chemical-toxicological analysis (November 2015 – January 2016)
Professional interests
Organic Chemistry, Medicinal Chemistry, Pharmaceutical Chemistry, Biology, Drug Development, Biochemistry.
CV
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