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Isabel Fernández

Main current position is not set

  • Joined: 2018
  • Items posted: 0
  • Profile views: 109

About

Summary

Skilled Researcher enthusiastic about supporting advancements in cancer research and expand my knowledge. Bringing experience in both self-directed and support research capacities. Proficient in molecular biology as in conducting laboratory experiments while informing on research methods and data collection procedures. Carrying computer skills (Office, SnapGene, FlowJo, Graphpad) and willing to continue learning. Hardworking and driven with superior organizational skills combined with dedication to research excellence.

Positions

Research Collaborator at the Pharmacognosy group Sep 2019 - Dec 2022

Switzerland

I started a complete new project to engineering multiple myeloma cell lines with CRISPR-Cas9 to generate models to test the specificity of compounds obtained from natural products and derivatives of them in the laboratory of Prof. Muriel Cuendet.

Postdoctoral Researcher at Gene expression Regulation & Cancer Group Jun 2018 - Sep 2019

Spain

I was involved in the analysis of deep sequencing, qPCR and western blot of several cell lines and tumors to define alterations on the SWI/SNF complex in lung adenocarcinoma. I also studied alterations in the expression of ncRNAs in lung cancer and pediatric B-cell acute lymphoblastic leukemia.

Predoctoral Researcher at the Gene expression Regulation & Cancer Group Jan 2014 - Jun 2018

Spain

Thesis: Study of the functional activity of microRNAs in lung cancer. Development of new therapeutic strategies.
Director: Prof. Pedro P. Medina
The SWI/SNF chromatin remodeling complex is altered in lung cancer. I revealed that the catalytic subunit SMARCA4 is inhibited by miR-155 in cell lines and patients samples. I also carried out a proof of concept to guide the expression of suicide genes towards tumor cells using an artificial 3'UTR with binding sites of let-7, a tumor suppressor microRNA that block the expression of the suicide gene in the normal cells.

Education

University of Almeria

Field of study: Chemistry
Degree: Licence

University of Granada

Field of study: Biochemistry and Molecular Biology
Degree: PhD

University of Granada

Field of study: Genetics
Degree: Master

CV

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New opportunities

Open to new opportunities: Yes

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