About
Summary
Biochemist with Structural Biology and Chemical Engineering background, currently in the process to defend my PhD in Molecular Biomedicine.
Skilled in protein expression, purification, crystallization and protein biochemistry.
Interested to pursue Postdoc research in
1. Ubiquitin-like and sulfur carrier proteins from all domains of life
2. Persulfidation- Evolutionary conserved protection mechanism against Oxidative Stress.
Positions
PhD Fellow/Student Oct 2017 - Dec 2022
Max Planck Research Group, Jagiellonian University
Research Scholar working on the project entitled “tRNA Modifications in Human Diseases-The structural and functional consequences of Urmylation in response to Oxidative stress”.
I hope to understand the nature of these ancient post-translational amendments, that stand at the interface amid prokaryotic sulfur relay systems and the eukaryotic ubiquitination pathway. Therefore, I aim to establish and optimize urmylation in vitro, recapitulate the regulatory networks under stress conditions and identify components that confer substrate specificity. The anticipated outcomes of this research work would afford profound molecular perceptions in to how urmylation auto-regulates Ahp1, Elongator, Uba4/Urm1-pathways and respective stress signaling pathways under oxidative stress conditions.
Graduate Research Intern Feb 2016 - Sep 2017
Graduate Research Intern under Dr. K.P. Gopinath, Associate Professor, Department of Chemical
Engineering, SSN College of Engineering, Chennai, India
Intern Objective: To perform growth and inhibition kinetic modeling for the wild and tolerant yeast strain against oxidative stress. (A collaborative research project between University of Nottingham and SSN College).
Graduate Research Intern Oct 2015 - Dec 2015
Bioenergy and Brewing Sciences Centre, University of Nottingham
Graduate Research Intern under Prof. Gregory Tucker, School of Biosciences and Queens Medical College, University of Nottingham, UK
Project Title: Study of oxidative stress tolerant Saccharomyces yeast.
Project Objective: ROS detection and Cell death analysis of the tolerant Saccharomyces spp. yeast against Oxidative stress using Flowcytometry
Research Assistant Jun 2013 - Jul 2014
Chemical Engineering, Adhiparasakthi Enngineering College
Research Assistant under Dr. G. Vijayaraghavan, Associate Professor, Department of Chemical
Engineering
Project Area: Feasibility studies on microalgae for bioremediation and biofuels .
Tasks and Responsibilities:
• Develop Research Protocols
• Assisting the research scholars
• Technical support to the project
• Laboratory maintenance
• Carrying out the experiments deputed by the Principal investigator
• Supervising undergraduate students working in the research project.
Education
Jagiellonian University 2017 - 2022
Field of study: Molecular Biomedicine, Structural Biochemistry
Degree: Doctor of Philosophy
Research Scholar working on the project entitled “tRNA Modifications in Human Diseases-The structural and functional consequences of Urmylation in response to Oxidative stress”.
I hope to understand the nature of these ancient post-translational amendments, that stand at the interface amid prokaryotic sulfur relay systems and the eukaryotic ubiquitination pathway. Therefore, I aim to establish and optimize urmylation in vitro, recapitulate the regulatory networks under stress conditions and identify components that confer substrate specificity. The anticipated outcomes of this research work would afford profound molecular perceptions in to how urmylation auto-regulates Ahp1, Elongator, Uba4/Urm1-pathways and respective stress signaling pathways under oxidative stress conditions.
University of Nottingham 2014 - 2015
Field of study: Sustainable bioenergy (Biosciences)
Degree: Master of Research
“Role of mitochondrial cytochrome C oxidase chaperone gene (COX20) in tolerance to hydrogen peroxide induced oxidative stress in Saccharomyces cerevisiae”
Anna University 2009 - 2013
Field of study: Chemical Engineering
Degree: Bachelors of Technology
Skills
Biochemistry, Molecular Biology, Molecular Cloning, Microbiology, Protein Expression, Protein Purification, Crystallization, Data Collection, Structural Biology, GraphPad Prism, Editorial Process,
Microsoft Tools, Adobe Tools, Scientific illustration, Soft skills, Leadership, Project Management, Patent filing, Project design and execution.
Professional interests
• Ubiquitin-like protein modifications in response to oxidative stress
• Sulfur carrier proteins roles in response to oxidative stress
• Archaeal Ubiquitin-like and sulfur carriers
• Oxidative stress, cancer and ageing
• Persulfidation- Evolutionary conserved protein protection mechanism against oxidative stress
• Reviewing and editorial process
Contact details
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