About
Summary
Postdoctoral Fellow with a demonstrated history of working in cancer biology. Now Trying to understand: what goes wrong which leads to Type-2 Diabetes, Molecular mechanisms of Glucolipotoxicity, ER stress, Mitochondrial redox state in health and disease.
Positions
Postdoc Fellow May 2018 -
Institute of Experimental and Clinical Research (IREC), Pole of Endocrinology, Diabetes and Nutrition, Université catholique de Louvain
As a Postdoc Fellow at UCLouvain, Brussels my main research interests are studying the molecular mechanisms of pancreatic beta cell dysfunction in type 2 Diabetes.
Postdoc Researcher May 2016 - Mar 2017
RIKEN Centre for Sustainable Resource Science, Riken
As a Postdoc Researcher at RIKEN my research interests were studying the the role of eIF5A post-translational modifications i.e. Acetylation and Hypusination. During this work I found that eIF5A plays important role in HIF-1α stabilization in hypoxia (BBRC 2016). I also found that eIF5A hypusination has an important role in mitochondrial metabolism (Unpublished).
Lecturer Dec 2010 - Sep 2012
Biotechnology, University of Malakand
Teaching courses of biotechnology by utilizing appropriate teaching, learning, support and assessment methods
• Undertaking marking, assessment and examination work and provision of timely feedback to students
• Conducting laboratory sessions
• Laboratory equipment and stock maintenance and ordering consumables
• Record keeping of consumables and reagents
Education
Saitama University, Japan 2012 - 2016
Field of study: Life Sciences
Degree: Doctor of Science
Thesis title "A novel role of eIF5A in HIF-1α-mediated hypoxic response"
Sheffield Hallam University, United Kingdom 2008 - 2009
Field of study: Pharmacology & Biotechnology
Degree: Master of Science
Thesis title "Expression of CASC2a In Different Endometrial Cancer Cell Lines"
University of Peshawar, Pakistan 2002 - 2006
Field of study: Biotechnology
Degree: Bachelor of Biotechnology
Skills
qPCR, Mammalian Cell Culture, Retroviral & Adenoviral Vector construction, Protein Isolation & Quantification, Western blotting, Immunoprecipitation, CRISPR/Cas9 gene editing, RT PCR, Molecular Cloning, Confocal Microscopy, Site Directed Mutagenesis, Hypoxia biology & HIF signaling, DNA transformation, RNAi knockdowns, 3D Cell culture, Human Islets culture, DNA & RNA extraction, Glucose-Stimulated Insulin Secretion (GSIS).
Keywords: Biochemistry , Cancer Research, Cellular Biology , CRISPRCas9, Epigenetics, gene cloning, Immunofluorescence (IF) staining, Immunohistochemistry (IHC), Molecular Biology, qPCR, RNA biology, Western blot