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Renata Marchette

Renata Marchette

Staff Scientist at National Institute of Health

  • Joined: 2017
  • Items posted: 0
  • Profile views: 134

About

Summary

I am a Pharmacist with master and doctorate degrees in Pharmacology.

During my undergrad Pharmacy course, I started as an intern in the Laboratory of Neuropsychopharmacology (UNESP, Araraquara) to study the potential of Brazilian medicinal plants in tests predictive for anxiolytic activity. Right after graduation I relocated to Florianopolis and started my Master in Pharmacology in which I worked in two projects, one of neuropharmacology screening of a Colombian passion fruit and the second, that became my Master’s thesis, in stress reactivity in female mice. After getting my diploma I got approved to the Ph.D. program to study mechanisms of resilience to stress in a mice social defeat model (Behav. Brain Res. 235 (2012) 55-66). During my Ph.D. I have mentored three undergrad students and established collaborations with two different labs. Also, I was a guest scientist in the LAboratoire de Pharmacologie de la Circulation Cérébale at the Univerté Paris Descartes for seven months, under the supervision of Professor Raymond Mongeau. I got my diploma in March 2017 and my thesis title is 'Resilience and vulnerability to social stress and its neurobiological implications'. 

Positions

Staff Scientist Mar 2024 -

National Institute on Drug Abuse, National Institute of Health

Postdoctoral Fellow Apr 2018 - Mar 2024

National Institute on Drug Abuse, National Institute of Health

PhD Student Oct 2015 - May 2016

Paris Descartes

Evidence suggests that PTSD and mild Traumatic Brain Injury (mTBI) have overlapping symptom profiles, share common mechanisms, and neural disturbances. In this project, we proposed to explore whether the combination of mTBI and subordination stress reduce mice capacity to perform fear extinction. This shall allow screening various pharmacological strategies for PTSD at the preclinical level.

PhD student Apr 2013 - Mar 2017

Departamento de Farmacologia, Universidade Federal de Santa Catarina

Resilience and vulnerability to social stress and its neurobiological implications
Investigation of the modulation of the HPA axis in a social defeat model and its role in stress resilience and susceptibility, and how it can be modulated by the neuropeptide substance P.

Education

Universidade Federal de Santa Catarina 2013 - 2017

Field of study: Pharmacology
Degree: Doctorate

Resilience and vulnerability to social stress and its neurobiological implications

Universidade Federal de Santa Catarina 2011 - 2013

Field of study: Pharmacology
Degree: Master

Temporal evaluation of the effects of stress on anxiety and depression-related behaviors in two mice strains, C57BL/6J and Swiss.
Evaluation of the influence of genetic background and stressor endurance on female mice in common tests of anxiety-like and depressive-like behavior.

Universidade Estadual Paulista 'Júlio de Mesquita Filho' 2006 - 2011

Field of study: Pharmacy and Biochemestry
Degree: Bachelor

Conclusion work: Evaluation of anxiolytic activity of the alkaloid fraction from Erythina velutina in mice submitted to the elevated plus maze and the light-dark transition test.

Skills

Behavioral tests (rodents), social defeat, mice breeding and care, western blotting, stereotaxic surgery, controlled cortical impact (TBI model), ELISA, immunofluorescence, PCR

Professional interests

Translational Psychiatry, Drug discovery, Pre-clinical studies, Neurocognition models, Behavior, Medicinal plants, Translational Neuroscience, Clinical trials, Behavioral Genetics

CV

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Contact details

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New opportunities

Open to new opportunities: Yes

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