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Sara Gomes

Sara Gomes

Main current position is not set

  • Joined: 2019
  • Items posted: 0
  • Profile views: 285

About

Summary

I have recently finished my PhD, which was focused on the pre-clinical validation of molecules that interfere with the p53 pathway in human cells and animal models, and am currently looking for postdoc positions.
 

Positions

PhD researcher Jan 2014 - Sep 2019

LAQV/REQUIMTE Laboratory of Microbiology, Faculty of Pharmacy, University of Porto

I have developed a PhD thesis focused on the pre-clinical validation of molecules that interfere with the p53 pathway in human cells and animal models. I have developed several techniques including recombinant protein production in bacterial systems, development of yeast model systems for screening of small molecules, analysis of cell cycle, apoptosis, gene and protein expression in human cells, co-immunoprecipitation, and chromatin immunoprecipitation. 

Education

Abel Salazar Institute of Biomedical Sciences of the University of Porto 2014 - 2019

Field of study: Cancer Pharmacology
Degree: Molecular and Cellular Biotechnology Applied to Health Sciences

Thesis title: Drugging p53-impaired tumors: impact of new small molecules targeting p73 and mutp53

Supervision: Lucília Saraiva, PhD. Assistant Professor, Faculty of Pharmacy University of Porto.

My PhD thesis focused on the identification and preclinical validation of new small molecules targeting p53 family proteins.

Faculty of Science University of Porto 2011 - 2013

Field of study: Biochemistry
Degree: MSc in Biochemistry

Thesis title: Studying p53 family proteins: search for small-molecule modulators

Supervision: Lucília Saraiva, PhD. Assistant Professor, Faculty of Pharmacy University of Porto.

My Master's thesis focused mainly on the development of yeast model systems to study and screen for pharmacological modulators of p53 family proteins.

Faculty of Science University of Porto 2008 - 2011

Field of study: Biochemistry
Degree: Degree in Biochemistry

Thesis title: Ionotropic P2X7 receptor favours osteogenic differentiation and membrane cell blebbing dynamics of human bone marrow stromal cells

Supervision: Maria Adelina Costa, PhD. Assistant Professor, Abel Salazar Institute of Biomedical Sciences, University of Porto.

The degree included a semester of research experience, in which I studied purinergic signalling pathways in primary cultures of human osteoblasts.

Skills

Cell Biology, Biochemistry, Cell Culture, Gene Expression, Protein Expression, Flow Cytometry, Fluorescence Microscopy, Western Blot, Microbiology, Cell Signalling, Humanized Yeast, Recombinant Protein Production

Professional interests

Cell Signalling, Neuroscience, Cancer Biology, Pharmacology, Basic Research, Metabolism

Contact details

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New opportunities

Open to new opportunities: Yes

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