About
Summary
Our research focuses on how somatic and stem cells integrate extracellular signals to modulate their fate
The architecture, homeostasis and function of the organs is defined at the cellular level by the integration of a myriad of molecular signals. In our lab, we study how stem cells, progenitor cells, and somatic cells integrate extracellular signals and how these cascades define cell fate. We focus on unravelling the molecular mechanisms underlying signal transduction, specially in ther context of the Wnt signalling pathway and mitosis. To address these questions we integrate cutting edge imaging and genome editing with detailed molecular analyses in mouse models, ex vivo cultured neural progenitor cells, organoids, as well as cell lines.