SOUNDARA RAJAN THANGAVELU

Summary

I am a Ph.D. graduate with a couple of years of post-doctoral research experiences in experimental neuroscience. I worked on investigating alternative therapy for neurodegenerative diseases using in vitro and in vivo models. Mesenchymal stem cells-secretome and phytocompounds had been used for my projects. At present, I am looking for a scientist or post-doctoral research fellow position in experimental neurology.

Positions

Education

Skills

Molecular biology: DNA/RNA/protein isolation & quantification from Bacteria and mammalian cells/tissues, primer designing, reverse transcription-PCR, real-time PCR and rodent tail genotyping.
Immunological techniques: Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western blotting and ELISA.
Cell/Tissue culture techniques: Primary and secondary culture establishment and maintenance. Mammalian cells: NSC34, RAW 264.7, C6, 1321N1, CCF-STTG1, and human gingival and periodontal ligament MSCs. Liposomal Transfection and clonal selection. Co-culture, conditioned medium and drug treatment with agonists/antagonists. In vitro neuroinflammatory, oxidative stress and scratch injury models. Lymphocytes extraction from human and rat blood.
Animal species handled/experiments: Rat (Wistar and Sprague-Dawley) and Mouse (C57Bl6 and 129 SV). Behavior studies: Pole test, Rotarod, Forced swim test, Elevated plus maze test, and gait and foot step length analyses. Disease model: MOG-induced experimental autoimmune encephalomyelitis (EAE), MPTP-induced Parkinson’s model and controlled cortical impact-traumatic brain injury. Human transgenic models: ALS and Dystonia. Repetitive transcranial magnetic stimulation in rodents.

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New opportunities

Open to new opportunities: Yes