About
Summary
Together with more than 7 years in medical research and development, I have involved in many projects in the field of biomedical sciences, molecular biology and biotechnology. I have studied in 5 different countries and successfully completed all objectives. I have solid knowledge and experience in molecular biology and imaging and as well as animal experimentation. I am open-minded to learn novel techniques in the field.
Positions
PhD Researcher Aug 2016 - Jun 2020
Medical faculty Mannheim, Heidelberg University
- Animal experimentation on (OB/OB rats, Hypertensive and diabetic rats)
- Evaluation of the kidney function in disease condition in rats.
- Evaluation of the histopathology of the kidney by use of (Confocal, light-sheet, super-resolution microscopy, and light microscopy)
- Statistical analysis of the obtained data (via JMP, SAS, and Excel)
- Developing a novel rat model to able to use in kidney research.
- Evaluation of histologic alterations.
- Investigating the effects of diabetes and hypertension on the kidney (especially in the filtration barrier of the kidney).
- Developing an imaging technique for the evaluation of nanoscale structures ( such as podocyte foot process) in the kidney.
- HK-2 cells culture to evaluate effect of high-low glucose.
Researcher Feb 2016 - Aug 2016
MSc Researcher, University of Naples Federico II
Biotechnology Laboratory:
- Propagation of colon cancer stem cells and brain tumor stem cells (BTSCs).
- Preparation of the media for cancer stem cells and cultivation.
- Knock-down and silencing the HMGA1 gene BTSCs
- Cell-Based Assays (cell viability and toxicity evaluation)
- Development of a protocol for the evaluation of the asymmetric cell division
- Evaluation of sphere forming efficiency in BTSCs
Research Trainee Feb 2015 - Aug 2015
Research Intern, Justus-Liebig-University
Cell Culture Laboratory
- Preparation of the differentiation media
- Propagation and freezing of the Adipose-derived stem cells (ASCs from dog)
- qPCR analysis for the adipogenic markers, and lipid staining
- Statistical evaluation of the qPCR results (quantitative, normalized quantitative analysis)
Clinical Research Associate Trainee Jun 2013 - Sep 2013
Cerrahpaşa Faculty of Medicine, Istanbul University
Embryology and Andrology Laboratory.
- Collecting the data from patients (occupation, drug usage, age. etc.)
- Data analysis for the success ratio
- Data analysis to determine the risk groups for the infertility
- Sperm Freezing and preservation
- Sperm Preparation for IUI
Erasmus Exchange Student Sep 2012 - Feb 2013
Education
Heidelberg University 2016 - 2020
Field of study: Experimental Medicine and Biotechnology
Degree: PhD
- Developing a novel rat model to able to use in kidney research.
- Evaluation of histologic alterations.
- Investigating the effects of diabetes and hypertension on the kidney (especially in the filtration barrier of the kidney).
- Developing an imaging technique for the evaluation of nanoscale structures ( such as podocyte foot process) in the kidney.
- HK-2 cells culture to evaluate the effect of high-low glucose.
Graduation: "magna cum laude"
University of Antwerp 2014 - 2016
Field of study: Biomedical Sciences
Degree: Master of Science - MSc
Eucomor (Erasmus Mundus Joint Master Programme) Biomedical Sciences:
- Advanced courses in molecular biology, cell biology, and animal science.
- Cancer biology and siRNA design
- Master Thesis: Effect of HMGA1 gene on Cell Fate Determinant Numb and Asymmetric
Cell Division in Brain Tumor Stem Cells.
Graduation: 85/100 - "Greatest Distinction"
Abant İzzet Baysal Üniversitesi 2010 - 2014
Field of study: Biology
Degree: Bachelor's degree
Molecular Biology
- Transfection and PCR techniques
- Cell culture methods
- Evolution and population genetics.
Skills
Keywords: Animal behavior, animal handling, Animal model, BioTechnology, Cell Biology , Cell Culture, cell lines, Cell migration, cell therapy, Cloning, DNA isolation, histology, JMP, Microsoft Office, Molecular Biology, molecular imaging, Molecular Medicine, organoids, PCR, PhD, physiology, Protein assay, qPCR, researcher, research scientist, RNA biology, RNA isolation, Western blotProfessional interests
- T-cell based cancer therapies
- Viral protein targetting via NGS
- mRNA based vaccine production
- Drug Discovery studies via NGS and RNA-seq
- Stem cell therapy
- Production of active enzymes via cell culture
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